Jiupeptide-1 is a biomimetic peptide that matches well with the MC1 receptor on melanocytes, making it a potent antagonist to melanocyte stimulating hormones. It competitively binds to the MC1 receptor, preventing further activation of tyrosinase and the production of melanin. The competitive chemobook of nine peptide-1 blocks the entry of receptors and various factor signals on melanocytes, weakening the activity of melanocytes and reducing melanin production. Starting from 14 days, the skin gradually becomes even, and after 28 days of a skin cycle, it significantly brightens the skin, presenting a rosy and fair complexion. Therefore, nine peptide-1 is often used as a cosmetic ingredient.