北京寰宇科创生物科技发展有限公司
| 中文名(CN) | 英文名(EN) | CAS No. | 规格(SP) | 报价(CNY) | 产地(From) | 类别(Key) |
| 6-氯-9-((4-甲氧基-3,5-二甲基-2-吡啶基)甲基)-9H-嘌呤-2-胺 | BIIB021,HPLC ≥99% | 848695-25-0 | 5MG | 980.00 | Bellancom-CN28733 | 标准品 |
| 6-氯-9-((4-甲氧基-3,5-二甲基-2-吡啶基)甲基)-9H-嘌呤-2-胺 | BIIB021,HPLC ≥99% | 848695-25-0 | 25MG | 2660.00 | Bellancom-CN28733 | 标准品 |
| 6-氯-9-((4-甲氧基-3,5-二甲基-2-吡啶基)甲基)-9H-嘌呤-2-胺 | BIIB021,HPLC ≥99% | 848695-25-0 | 100MG | 7300.00 | Bellancom-CN28733 | 标准品 |
数据参数(Specifications)
免费开具北京商业企业专用发票，签订正规销售合同，Bellcom正品保证，免费技术支持，免收境内运费。| 中文名称 | BIIB-021; BIIB 021; 6-氯-9-((4-甲氧基-3,5-二甲基-2-吡啶基)甲基)-9H-嘌呤-2-胺 |
| 英文名称 | CNF2024; ;CNF 2024;CNF-2024;6-chloro-9-((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)-9h-purin-2-amine;1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)pheny |
| CAS识别号 | 848695-25-0 |
| MDL识别号 | Null,without related properties. |
| EC识别号 | Null,without related properties. |
| Beilstein | Null,without related properties. |
| 分子式 | C14H15ClN6O |
| 分子量 | 318.77 |
| 分子结构图 |  |
| 产品性状 | BIIB021(CNF2024)是口服活性的HSP90抑制剂，Ki和EC50分别为1.7 nM和38 nM。溶解性：DMSO ≥60mg/mL Water <1.2mg/mL Ethanol ≥1.8mg/mL |
| 质量标准 | Oral administration of BIIB021 leads to tumor growth inhibition in many tumor xenograft models including N87, BT474, CWR22, U87, SKOV3 and Panc-1. BIIB021 effectively inhibits growth of L540cy tumor at a dose of 120 mg/kg. BIIB021 significantly enhances antitumor growth effect of radiation in JHU12 xenograft. |
| 储存条件 | -20 °C 冷藏保存，Stored at -20 °C |
