产品基本信息:
中文名称:18碳烷基链-聚乙二醇-苯硼酸
英文简称:C18-PEG-PBA
分子量:400 600 1000 2000 3400 5000 10000
性状:根据分子量,呈现粘稠液体或固体粉末。
产品纯度:95%
品牌:齐岳生物
产地:西安
含量:95%
用途:科研
产品规格:1g/5g/10g
保存时间:一年
保存取用:缓慢恢复至室温,取用后充入惰性气体,冷冻保存。
应用简介:Phenylboronic acid (PBA) is a tumor targeting molecule, but its nonspecific interaction with normal cells or other components containing cis-diol residues undoubtedly limits its potential application in tumor targeting drug delivery. Herein, we developed fructose-coated mixed micelles via PBA-terminated polyethylene glycol monostearate (PBA-PEG-C18) and Pluronic P123 (PEG20-PPG70-PEG20) to solve this problem, as the stability of borate formed by PBA and fructose was dramatically dependent on pH. The fluorescence spectroscopic results indicated that the borate formed by PBA and fructose decomposed at a decreased pH, and better binding between PBA and sialic acid (SA) was observed at a low pH. These results implied that the fructose groups decorated on the surface of the micelles could be out-competed by SA at a low pH.
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温馨提示:西安齐岳生物科技有限公司供应的产品仅用于科研,不能用于其他用途,axc,2020.01.06